منابع مشابه
Free radicals in cerebral ischemia.
The possibility that cerebral ischemia may initiate a series of pathological free radical reactions within the membrane components of the CNS was investigated in the cat. The normally occurring electron transport radicals require adequate molecular oxygen for orderly transport of electrons and protons. A decrease in tissue oxygen removes the controls over the electron transport radicals, and al...
متن کاملOxygen radicals in cerebral ischemia.
Superoxide production was measured as the superoxide dismutase (SOD)-inhibitable portion of nitro blue tetrazolium (NBT) reduction after cerebral ischemia-reperfusion in anesthetized cats equipped with cranial windows. Significant superoxide production was found in the early reperfusion period and continued for more than 1 h after ischemia. Superoxide was not detected in control animals not sub...
متن کاملFree radicals in central nervous system ischemia.
Free radicals have been implicated in a wide variety of diseases and in the toxic and therapeutic effects of antineoplastic drugs and radiation, the deleterious consequences of environmental pollutants, and "degenerative" processes such as aging and Parkinson's disease.Their involvement in myocardial and intestinal as well as central nervous system (CNS) ischemia is under intensive study. A fre...
متن کاملCerebral ischaemia, free radicals and antioxidant protection.
22. Beckman, J. S. (1990) Nature (London) 345,27-28 23. Beckman, J. S. (1991) J. Dev. Physiol. 15, 53-59 24. Dawson, V. I,., Dawson, T. M., London, E. D., Brent, D. S. and Snyder, S. H. (1991) Proc. Natl. Acad. Sci. U.S.A. 88,6368-6371 25. Matheis, G., Sherman, M. P., Buckberg, G. D., Haybron, D. M., Young, H. H. and Ignarro, L. J. (1 992) Amer J. Physiol. 262, H616-H620 26. Mulligan, M. S., He...
متن کاملIschemia-induced norepinephrine release, but not norepinephrine-derived free radicals, contributes to myocardial ischemia-reperfusion injury.
BACKGROUND Norepinephrine (NE)-derived free radicals may contribute to myocyte injury after ischemia -reperfusion, so the influence of sympathetic denervation on myocardial ischemia - reperfusion injury was investigated in the present study. METHODS AND RESULTS Cardiac sympathetic denervation was produced in Wistar rats by a solution of 10% phenol 1 week before ischemia. Atenolol (0.5 mg/kg) ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stroke
سال: 1978
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.9.5.445